Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | VCP | P55072 | 7/20 | 0.46 |
| ▸ | KDR | P35968 | 7/20 | 0.45 |
| ▸ | FLT1 | P17948 | 6/20 | 0.45 |
| ▸ | FLT4 | P35916 | 5/20 | 0.45 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.43 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.43 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925625 | 0.87 | ALOX5 (0.66) | ALOX5VCPKDRFLT1FLT4 | |
| SCHEMBL29620955 | 0.81 | VCP (0.50) | ALOX5VCPKDRFLT1FLT4 | |
| SCHEMBL22925943 | 0.81 | VCP (0.50) | ALOX5VCPKDRFLT1FLT4 | |
| SCHEMBL22925953 | 0.80 | ALOX5 (0.47) | ALOX5VCPKDRFLT1FLT4 | |
| SCHEMBL29696271 | 0.80 | ALOX5 (0.47) | ALOX5VCPKDRFLT1FLT4 | |
| SCHEMBL22925621 | 0.80 | ALOX5 (0.51) | ALOX5VCPKDRFLT1FLT4 | |
| SCHEMBL29620865 | 0.72 | VCP (0.40) | ALOX5VCPKDRFLT1PRKAB2 | |
| SCHEMBL28733697 | 0.72 | VCP (0.40) | ALOX5VCPKDRFLT1PRKAB2 | |
| SCHEMBL22925593 | 0.72 | ALOX5 (0.43) | ALOX5VCPKDRFLT1FLT4 | |
| SCHEMBL14438058 | 0.70 | PTGS2 (0.51) | KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012018-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2021-01-28 | — | — | WO | disclosed |