Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 6/20 | 0.41 |
| ▸ | FLT1 | P17948 | 5/20 | 0.41 |
| ▸ | FLT4 | P35916 | 5/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.39 |
| ▸ | VCP | P55072 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925713 | 1.00 | HDAC1 (0.44) | HDAC1TRPV1ALOX5KDRFLT1 | |
| SCHEMBL22925710 | 0.85 | TRPV1 (0.47) | HDAC1TRPV1ALOX5KDRFLT1 | |
| SCHEMBL28939281 | 0.85 | TRPV1 (0.47) | HDAC1TRPV1ALOX5KDRFLT1 | |
| SCHEMBL22925942 | 0.85 | TRPV1 (0.47) | HDAC1TRPV1ALOX5KDRFLT1 | |
| SCHEMBL24636947 | 0.79 | ALOX5 (0.47) | TRPV1ALOX5KDRFLT1FLT4 | |
| SCHEMBL22925716 | 0.74 | KDR (0.49) | HDAC1TRPV1ALOX5KDRFLT1 | |
| SCHEMBL22926117 | 0.71 | TRPV1 (0.45) | HDAC1TRPV1ALOX5KDRFLT1 | |
| Hydrochloric Acid SCHEMBL31707411 | 0.71 | TRPV1 (0.45) | HDAC1TRPV1ALOX5KDRFLT1 | |
| SCHEMBL22925593 | 0.68 | ALOX5 (0.43) | ALOX5KDRFLT1FLT4IMPDH2 | |
| SCHEMBL22925699 | 0.67 | VCP (0.60) | TRPV1ALOX5KDRFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012018-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2021-01-28 | — | — | WO | disclosed |