Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.49 |
| ▸ | FLT1 | P17948 | 6/20 | 0.49 |
| ▸ | FLT4 | P35916 | 6/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24636894 | 0.83 | TRPV1 (0.49) | KDRFLT1FLT4IMPDH2TRPV1 | |
| SCHEMBL22925713 | 0.74 | HDAC1 (0.44) | KDRFLT1FLT4ACHEIMPDH2 | |
| SCHEMBL14134354 | 0.74 | KDR (0.73) | KDRFLT1FLT4IMPDH2ALOX5 | |
| SCHEMBL22925717 | 0.74 | HDAC1 (0.44) | KDRFLT1FLT4ACHEIMPDH2 | |
| SCHEMBL2925824 | 0.72 | KDR (0.55) | KDRFLT1FLT4IMPDH2TRPV1 | |
| SCHEMBL5502444 | 0.70 | ALOX5 (0.56) | KDRFLT1FLT4IMPDH2ALOX5 | |
| SCHEMBL2924685 | 0.70 | FLT1 (0.49) | KDRFLT1FLT4IMPDH2ALOX5 | |
| SCHEMBL2345680 | 0.70 | KDR (0.51) | KDRFLT1FLT4IMPDH2TRPV1 | |
| SCHEMBL2926789 | 0.69 | KDR (0.71) | KDRFLT1FLT4IMPDH2ALOX5 | |
| SCHEMBL4748476 | 0.69 | ALDH1A1 (0.52) | KDM4EALDH1A1GAANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012018-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2021-01-28 | — | — | WO | disclosed |