Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 5/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.36 |
| ▸ | ULK1 | O75385 | 2/20 | 0.36 |
| ▸ | VCP | P55072 | 3/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29620908 | 1.00 | GCGR (0.39) | GCGRKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL22925753 | 1.00 | GCGR (0.39) | GCGRKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL22925647 | 0.90 | VCP (0.40) | GCGRALOX5MAP2K1ULK1VCP | |
| SCHEMBL29620865 | 0.90 | VCP (0.40) | GCGRALOX5MAP2K1ULK1VCP | |
| SCHEMBL28733697 | 0.90 | VCP (0.40) | GCGRALOX5MAP2K1ULK1VCP | |
| SCHEMBL22925675 | 0.87 | TRPV1 (0.40) | GCGRTRPV1ALOX5VCP | |
| SCHEMBL29620976 | 0.87 | TRPV1 (0.40) | GCGRTRPV1ALOX5VCP | |
| SCHEMBL22925985 | 0.87 | TRPV1 (0.40) | GCGRTRPV1ALOX5VCP | |
| SCHEMBL22925988 | 0.87 | TRPV1 (0.40) | GCGRTRPV1ALOX5VCP | |
| SCHEMBL29620979 | 0.87 | TRPV1 (0.40) | GCGRTRPV1ALOX5VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220274970-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-09-01 | — | — | US | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |
| WO-2021012018-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2021-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220274970-A1 | INHIBITOR COMPOUNDS | SERPINB1, MMP1, SSB | GCGR 3791/4885KCNQ3 4747/4885KCNQ2 4731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.