Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 5/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.49 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 5/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925707 | 1.00 | CSF1R (0.49) | CSF1RNTRK1NTRK3NTRK2NPC1 | |
| SCHEMBL22969739 | 0.85 | NPC1 (0.46) | CSF1RNTRK1NTRK3NTRK2NPC1 | |
| SCHEMBL27107675 | 0.85 | NPC1 (0.46) | CSF1RNTRK1NTRK3NTRK2NPC1 | |
| SCHEMBL22925872 | 0.82 | MAOB (0.50) | CSF1RNPC1RAB9AAPPMAOB | |
| SCHEMBL29620984 | 0.82 | MAOB (0.50) | CSF1RNPC1RAB9AAPPMAOB | |
| SCHEMBL9366721 | 0.78 | NPC1 (0.47) | CSF1RNTRK1NTRK3NTRK2NPC1 | |
| SCHEMBL15633170 | 0.78 | APP (0.54) | NPC1RAB9AAPPMAOBSMN1; SMN2 | |
| SCHEMBL23663289 | 0.77 | ABCB1 (0.49) | NPC1RAB9AMAOBABCB1SMN1; SMN2 | |
| SCHEMBL29965423 | 0.77 | ABCB1 (0.49) | NPC1RAB9AMAOBABCB1SMN1; SMN2 | |
| SCHEMBL25180595 | 0.76 | CCR5 (0.57) | CSF1RNTRK1NTRK3NTRK2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |