Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.49 |
| ▸ | KIT | P10721 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 5/20 | 0.46 |
| ▸ | FLT1 | P17948 | 4/20 | 0.46 |
| ▸ | FLT4 | P35916 | 4/20 | 0.46 |
| ▸ | VCP | P55072 | 1/20 | 0.41 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24637048 | 0.84 | ALOX5 (0.55) | ALOX5TRPV1KITKDRFLT1 | |
| SCHEMBL22925577 | 0.82 | ALOX5 (0.53) | ALOX5TRPV1KITKDRFLT1 | |
| SCHEMBL22925621 | 0.82 | ALOX5 (0.51) | ALOX5TRPV1KITKDRFLT1 | |
| SCHEMBL26307279 | 0.82 | FLT1 (0.52) | ALOX5TRPV1KDRFLT1FLT4 | |
| SCHEMBL22925990 | 0.81 | ALOX5 (0.51) | ALOX5TRPV1KITKDRFLT1 | |
| SCHEMBL14134241 | 0.81 | KDR (0.73) | ALOX5TRPV1KITKDRFLT1 | |
| SCHEMBL29620925 | 0.78 | TRPV1 (0.48) | ALOX5TRPV1KITKDRFLT1 | |
| SCHEMBL22925553 | 0.78 | TRPV1 (0.49) | ALOX5TRPV1KDRFLT1FLT4 | |
| SCHEMBL22925652 | 0.78 | TRPV1 (0.50) | ALOX5TRPV1KDRFLT1FLT4 | |
| SCHEMBL23540014 | 0.77 | VCP (0.69) | ALOX5TRPV1KDRFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012018-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2021-01-28 | — | — | WO | disclosed |