Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.50 |
| ▸ | KDR | P35968 | 4/20 | 0.47 |
| ▸ | FLT1 | P17948 | 3/20 | 0.47 |
| ▸ | FLT4 | P35916 | 3/20 | 0.47 |
| ▸ | VCP | P55072 | 4/20 | 0.46 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925621 | 0.85 | ALOX5 (0.51) | TRPV1KDRFLT1FLT4VCP | |
| SCHEMBL22925553 | 0.82 | TRPV1 (0.49) | TRPV1KDRFLT1FLT4VCP | |
| SCHEMBL22925839 | 0.82 | KMT2A (0.52) | TRPV1KDRFLT1FLT4VCP | |
| SCHEMBL23540651 | 0.82 | VCP (0.69) | TRPV1KDRFLT1FLT4VCP | |
| SCHEMBL26307279 | 0.82 | FLT1 (0.52) | TRPV1KDRFLT1FLT4VCP | |
| SCHEMBL23540014 | 0.82 | VCP (0.69) | TRPV1KDRFLT1FLT4VCP | |
| SCHEMBL22925496 | 0.81 | TRPV1 (0.47) | TRPV1KDRFLT1FLT4VCP | |
| SCHEMBL29620967 | 0.81 | TRPV1 (0.47) | TRPV1KDRFLT1FLT4VCP | |
| SCHEMBL22925576 | 0.81 | TRPV1 (0.47) | TRPV1KDRFLT1FLT4VCP | |
| SCHEMBL22925769 | 0.80 | TRPV1 (0.45) | TRPV1KDRFLT1FLT4VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001870-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2026-01-01 | — | — | US | disclosed |
| US-12448371-B2 | Inhibitor compounds | Cincera Therapeutics Pty Ltd (AU) | 2025-10-21 | — | — | US | disclosed |
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| US-20220274970-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-09-01 | — | — | US | disclosed |
| US-20220274970-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-09-01 | — | — | US | disclosed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |
| WO-2021012018-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2021-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220274970-A1 | INHIBITOR COMPOUNDS | SERPINB1, MMP1, SSB | TRPV1 4690/4885KDR 3951/4885FLT1 2567/4885 |
| US-20260001870-A1 | INHIBITOR COMPOUNDS | CES1, NCEH1, NR1H2 | TRPV1 3641/4885KDR 3311/4885FLT1 2182/4885 |
| US-12448371-B2 | Inhibitor compounds | SERPINB1, MMP1, SSB | TRPV1 4690/4885KDR 3951/4885FLT1 2567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.