Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.39 |
| ▸ | FLT1 | P17948 | 4/20 | 0.38 |
| ▸ | FLT4 | P35916 | 4/20 | 0.38 |
| ▸ | KDR | P35968 | 4/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28733678 | 1.00 | NPSR1 (0.39) | NPSR1TRPV1FLT1FLT4KDR | |
| SCHEMBL29620970 | 1.00 | NPSR1 (0.39) | NPSR1TRPV1FLT1FLT4KDR | |
| SCHEMBL29696304 | 0.89 | IMPDH2 (0.43) | NPSR1TRPV1FLT1FLT4KDR | |
| SCHEMBL22926080 | 0.89 | IMPDH2 (0.43) | NPSR1TRPV1FLT1FLT4KDR | |
| SCHEMBL28733676 | 0.87 | TRPV1 (0.41) | TRPV1FLT1FLT4KDRGSK3B | |
| SCHEMBL22926054 | 0.82 | GSK3B (0.41) | TRPV1FLT1FLT4KDRGSK3B | |
| SCHEMBL29621081 | 0.82 | GSK3B (0.41) | TRPV1FLT1FLT4KDRGSK3B | |
| SCHEMBL22925705 | 0.82 | FLT1 (0.46) | TRPV1FLT1FLT4KDRGSK3B | |
| SCHEMBL31755987 | 0.80 | TRPV1 (0.39) | TRPV1FLT1FLT4KDRGSK3B | |
| SCHEMBL22925756 | 0.80 | NPSR1 (0.43) | NPSR1FLT1FLT4KDRGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012018-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2021-01-28 | — | — | WO | disclosed |