Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 6/20 | 0.46 |
| ▸ | FLT4 | P35916 | 6/20 | 0.46 |
| ▸ | KDR | P35968 | 6/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 2/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925873 | 0.89 | IMPDH2 (0.45) | FLT1FLT4KDRIMPDH2TRPV1 | |
| SCHEMBL29696276 | 0.86 | TRPV1 (0.42) | FLT1FLT4KDRIMPDH2TRPV1 | |
| SCHEMBL31755987 | 0.85 | TRPV1 (0.39) | FLT1FLT4KDRIMPDH2TRPV1 | |
| SCHEMBL22926054 | 0.84 | GSK3B (0.41) | FLT1FLT4KDRIMPDH2TRPV1 | |
| SCHEMBL29621081 | 0.84 | GSK3B (0.41) | FLT1FLT4KDRIMPDH2TRPV1 | |
| SCHEMBL28733676 | 0.82 | TRPV1 (0.41) | FLT1FLT4KDRIMPDH2TRPV1 | |
| SCHEMBL22926050 | 0.82 | NPSR1 (0.39) | FLT1FLT4KDRIMPDH2TRPV1 | |
| SCHEMBL29620970 | 0.82 | NPSR1 (0.39) | FLT1FLT4KDRIMPDH2TRPV1 | |
| SCHEMBL28733678 | 0.82 | NPSR1 (0.39) | FLT1FLT4KDRIMPDH2TRPV1 | |
| SCHEMBL22925774 | 0.80 | TRPV1 (0.48) | FLT1FLT4KDRIMPDH2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |
| WO-2021012018-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2021-01-28 | — | — | WO | disclosed |