Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.70 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | AHR | P35869 | 1/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22926421 | 0.84 | TAAR1 (0.64) | HTTTAAR1RAB9ANPC1MEN1 | |
| SCHEMBL824577 | 0.84 | KMT2A (0.69) | HTTTAAR1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL22926673 | 0.82 | TAAR1 (1.00) | HTTTAAR1RAB9ANPC1MEN1 | |
| SCHEMBL17609477 | 0.82 | RAB9A (1.00) | HTTRAB9ASMN1; SMN2NPC1GAA | |
| Water SCHEMBL30430295 | 0.81 | HTT (0.97) | HTTTAAR1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL22926426 | 0.81 | TAAR1 (0.80) | HTTTAAR1RAB9ANPC1MEN1 | |
| SCHEMBL27193044 | 0.80 | RAB9A (0.77) | HTTRAB9ASMN1; SMN2NPC1GAA | |
| SCHEMBL30051982 | 0.80 | MEN1 (0.77) | HTTTAAR1RAB9ANPC1MEN1 | |
| SCHEMBL9637653 | 0.80 | MEN1 (0.77) | HTTTAAR1RAB9ANPC1MEN1 | |
| SCHEMBL14062228 | 0.79 | GAA (0.76) | RAB9ASMN1; SMN2NPC1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210022340-A1 | USE OF PYRIDINE UREA COMPOUND HAVING SNAIL-KILLING ACTIVITY | THE NATIONAL INSTITUTE OF PARASITIC DISEASES, CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION (CN) | 2021-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210022340-A1 | USE OF PYRIDINE UREA COMPOUND HAVING SNAIL-KILLING ACTIVITY | SLC14A1, UACA, UROD | HTT 4212/4885TAAR1 3950/4885RAB9A 1093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.