SCHEMBL22926907

SCHEMBL22926907

c1ccc(-c2ccc(-n3c4ccccc4c4cc5c6cc7ccccc7cc6n(-c6ccccc6)c5cc43)c3ccccc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
KDM4E B2RXH2 2/20 0.46
ATM Q13315 1/20 0.46
HTR6 P50406 3/20 0.35
KMT2A Q03164 3/20 0.35
IL1R1 P14778 1/20 0.35
ALDH1A1 P00352 4/20 0.34
MEN1 O00255 2/20 0.34
MAPT P10636 2/20 0.34
HTT P42858 1/20 0.34
KDR P35968 1/20 0.34
TSHR P16473 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
HSD17B10 Q99714 1/20 0.31
HPGD P15428 1/20 0.31
MPI P34949 1/20 0.31
PTPN1 P18031 1/20 0.30
MAPK14 Q16539 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23604347 0.93 L3MBTL1 (0.53) L3MBTL1KDM4EATMHTR6KMT2A
SCHEMBL23203968 0.91 L3MBTL1 (0.50) L3MBTL1KDM4EATMHTR6KMT2A
SCHEMBL25098402 0.90 L3MBTL1 (0.46) L3MBTL1KDM4EATMHTR6KMT2A
SCHEMBL19637663 0.89 KDM4E (0.41) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL19637608 0.89 KDM4E (0.41) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL23604056 0.88 L3MBTL1 (0.46) L3MBTL1KDM4EATMHTR6KMT2A
SCHEMBL22186435 0.88 KDM4E (0.42) L3MBTL1KDM4EATMHTR6KMT2A
SCHEMBL23309126 0.88 L3MBTL1 (0.44) L3MBTL1KDM4EATMHTR6KMT2A
SCHEMBL19637664 0.87 KDM4E (0.39) L3MBTL1KDM4EATMHTR6KMT2A
SCHEMBL19636952 0.87 KDM4E (0.39) L3MBTL1KDM4EATMHTR6KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329107-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-10-12 US disclosed
US-11706984-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-07-18 US disclosed
US-11706984-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-07-18 US disclosed
US-20220384744-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-12-01 US disclosed
US-20210193933-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2021-06-24 US disclosed
US-20210126203-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2021-04-29 US disclosed
US-20210028373-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210028373-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TERT, TELO2, LIMS1 L3MBTL1 46/4885KDM4E 3066/4885ATM 2257/4885
US-20220384744-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TELO2, PIEZO1, LIMS1 L3MBTL1 32/4885KDM4E 3633/4885ATM 3542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.