SCHEMBL22926992

SCHEMBL22926992

c1cc(-c2cccc3c2oc2ccccc23)cc(-n2c3ccc4ccccc4c3c3ccc4ccccc4c32)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.44
GGPS1 O95749 1/20 0.39
PRKDC P78527 6/20 0.38
PTGES2 Q9H7Z7 1/20 0.36
PRMT5 O14744 1/20 0.36
WDR77 Q9BQA1 1/20 0.36
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CYP1A1 P04798 3/20 0.33
CYP1A2 P05177 3/20 0.33
CYP1B1 Q16678 2/20 0.33
PIK3CD O00329 1/20 0.33
PIK3CB P42338 1/20 0.33
ATM Q13315 1/20 0.32
FYN P06241 1/20 0.32
MAPK3 P27361 1/20 0.32
AHR P35869 1/20 0.32
PAX8 Q06710 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
SIRT2 Q8IXJ6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22960403 0.90 ALOX5 (0.39) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL22926973 0.90 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL20029544 0.90 ALOX5 (0.41) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL22927000 0.89 TDP1 (0.39) ALOX5TDP1L3MBTL1CYP1A1CYP1A2
SCHEMBL17341450 0.88 ALOX5 (0.36) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL25098650 0.85 ALOX5 (0.34) ALOX5GGPS1PRKDCSIRT2SIRT1
SCHEMBL23961027 0.84 CDK4 (0.35) TDP1CYP1A1CYP1A2CYP1B1FYN
SCHEMBL20029599 0.83 ALOX5 (0.42) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL22186604 0.83 ALOX5 (0.40) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL22186221 0.83 ALOX5 (0.40) ALOX5GGPS1PRKDCPTGES2PRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329107-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-10-12 US disclosed
US-20230329107-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-10-12 US disclosed
US-11706984-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-07-18 US disclosed
US-11706984-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-07-18 US disclosed
US-20220384744-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-12-01 US disclosed
US-20210193933-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2021-06-24 US disclosed
US-20210126203-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2021-04-29 US disclosed
US-20210028373-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210028373-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TERT, TELO2, LIMS1 ALOX5 956/4885GGPS1 426/4885PRKDC 4087/4885
US-20220384744-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TELO2, PIEZO1, LIMS1 ALOX5 506/4885GGPS1 341/4885PRKDC 4300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.