Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21706214 | 1.00 | NOTUM (0.38) | NOTUMALOX15HSD17B10POLBHDAC8 | |
| SCHEMBL21211796 | 0.95 | NOTUM (0.39) | NOTUMALOX15HSD17B10MEN1KMT2A | |
| SCHEMBL31267467 | 0.91 | GLA (0.37) | NOTUMHSD17B10MEN1KMT2A | |
| SCHEMBL31267490 | 0.91 | GLA (0.37) | NOTUMHSD17B10MEN1KMT2A | |
| SCHEMBL31208371 | 0.91 | GLA (0.37) | NOTUMHSD17B10MEN1KMT2A | |
| SCHEMBL31267479 | 0.91 | GLA (0.37) | NOTUMHSD17B10MEN1KMT2A | |
| SCHEMBL21211613 | 0.90 | HTR7 (0.36) | POLB | |
| SCHEMBL29308553 | 0.88 | UBE2M (0.34) | NOTUMSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23085135 | 0.87 | CXCR4 (0.37) | NOTUM | |
| SCHEMBL29308576 | 0.86 | SLC6A4 (0.34) | NOTUMSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12036289-B2 | Gadolinium bearing PCTA-based contrast agents | BRACCO IMAGING S.P.A. (IT) | 2024-07-16 | — | — | US | disclosed |
| EP-3770160-A1 | GADOLINIUM BEARING PCTA-BASED CONTRAST AGENTS | Bracco Imaging SPA (IT) | 2021-01-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12036289-B2 | Gadolinium bearing PCTA-based contrast agents | GLRX3, GLRA1, GRHPR | NOTUM 4170/4885ALOX15 4631/4885HSD17B10 2337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.