SCHEMBL2292794

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1201118	0.90	CDK4 (0.41)	PTGER1PTGER4PTGER3PTGER2MAOA
	SCHEMBL2287699	0.89	ALDH1A1 (0.43)	SCN8APPARGALDH1A1L3MBTL1NPC1
	SCHEMBL1199640	0.88	MAPT (0.37)	SCN8APTGER1PTGER4PTGER3PTGER2
	SCHEMBL2294471	0.87	ALDH1A1 (0.42)	SCN8APTGER1PTGER4PTGER3PTGER2
	SCHEMBL2288078	0.86	FFAR1 (0.42)	PPARGALDH1A1CDK4CCND1CCNB2
	SCHEMBL2293617	0.83	TRIM24 (0.49)	SCN8AALDH1A1NPC1RAB9ACDK4
	SCHEMBL2289750	0.82	CCNB2 (0.40)	MAOAMAOBALDH1A1L3MBTL1CDK4
	SCHEMBL1201385	0.81	SCN8A (0.46)	SCN8APTGER4MAOBPPARGALDH1A1
	SCHEMBL2292473	0.81	SCN8A (0.39)	SCN8APTGER1PTGER4PTGER3PTGER2
	SCHEMBL2295498	0.81	NPSR1 (0.36)	MAOAMAOBPPARGALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.