SCHEMBL1201385

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1200538	0.90	SCN8A (0.37)	SCN8APOLBMAPTCHRM5FFAR4
	SCHEMBL2288070	0.84	POLB (0.37)	SCN8APOLBMAPTFFAR4CCNB2
	SCHEMBL2293617	0.84	TRIM24 (0.49)	SCN8APOLBMAPTCCNB2CDK1
	SCHEMBL28783220	0.83	POLB (0.38)	SCN8APOLBMAPTFFAR4CYP3A4
	SCHEMBL2289750	0.83	CCNB2 (0.40)	POLBMAPTCHRM2CHRM1CHRM3
	SCHEMBL1199640	0.81	MAPT (0.37)	SCN8APOLBMAPTPTGER4CCNB2
	SCHEMBL2292794	0.81	SCN8A (0.39)	SCN8APOLBMAPTMAOBPTGER4
	SCHEMBL1200926	0.81	LMNA (0.43)	POLBMAPTMAOBCYP3A4MEN1
	SCHEMBL1201118	0.81	CDK4 (0.41)	FFAR4MAOBPTGER4CCNB2CDK1
	SCHEMBL1200524	0.81	CDK4 (0.38)	SCN8APOLBMAPTMAOBCCNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.