Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26968829 | 0.80 | THRB (0.53) | THRBALDH1A1LMNA | |
| SCHEMBL8224176 | 0.75 | — | — | |
| SCHEMBL735364 | 0.72 | THRB (0.36) | THRBALDH1A1LMNA | |
| SCHEMBL735390 | 0.72 | THRB (0.36) | THRBALDH1A1LMNA | |
| SCHEMBL735363 | 0.72 | THRB (0.36) | THRBALDH1A1LMNA | |
| SCHEMBL4286914 | 0.72 | — | — | |
| SCHEMBL8841215 | 0.71 | LMNA (0.38) | THRBALDH1A1LMNA | |
| SCHEMBL17833166 | 0.70 | THRB (0.42) | THRBALDH1A1LMNA | |
| SCHEMBL19708220 | 0.70 | THRB (0.42) | THRBALDH1A1LMNA | |
| SCHEMBL26894517 | 0.70 | CA12 (0.48) | THRBALDH1A1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3380101-B1 | EIF4-A-INHIBITING COMPOUNDS AND METHODS RELATED THERETO | EFFECTOR THERAPEUTICS INC (US) | 2021-01-27 | — | — | EP | disclosed |