Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14663224 | 0.81 | LMNA (0.44) | LMNAALDH1A1THRBTYMP | |
| SCHEMBL19708448 | 0.81 | MEN1 (0.44) | LMNAALDH1A1THRBMEN1OPRM1 | |
| SCHEMBL2231452 | 0.79 | — | — | |
| SCHEMBL13424894 | 0.79 | — | — | |
| SCHEMBL13424897 | 0.79 | — | — | |
| SCHEMBL2232621 | 0.78 | LMNA (0.53) | LMNAALDH1A1THRBTYMP | |
| Hydrochloric Acid SCHEMBL28419848 | 0.76 | PKM (0.32) | — | |
| SCHEMBL3754712 | 0.75 | LMNA (0.50) | LMNAALDH1A1THRBTYMP | |
| Hydrochloric Acid SCHEMBL7626501 | 0.75 | LMNA (0.50) | LMNAALDH1A1THRBTYMP | |
| SCHEMBL3424464 | 0.75 | LMNA (0.38) | LMNAALDH1A1THRBTYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616798-A | 2,2',4,4'6,6'-HEXAAMIDO-3,3',5,5'-TETRAIODOBIPHENYLS; RADIOLOGY | GUERBET S.A. (FR) | 1997-04-01 | — | — | US | disclosed |
| WO-1992014695-A1 | NEW POLYIODATED COMPOUNDS, METHOD OF PREPARATION, CONTRAST PRODUCT CONTAINING THEM | GUERBET S.A. (FR) | 1992-09-03 | — | — | WO | disclosed |
| EP-0501875-A1 | Poly-iodinated compounds, process of preparation, contrast agents containing them | GUERBET S.A. (FR) | 1992-09-02 | — | — | EP | disclosed |