Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2295166 | 0.81 | FGFR1 (0.46) | ALDH1A1HPGDMAPTGAAFGFR1 | |
| SCHEMBL9232435 | 0.81 | ALDH1A1 (0.61) | PKMALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL12732375 | 0.78 | ALDH1A1 (0.56) | PKMALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL29613728 | 0.78 | ALDH1A1 (0.56) | PKMALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL2298645 | 0.77 | NPC1 (0.56) | HPGDKMT2AMAPTGAAMEN1 | |
| SCHEMBL19911386 | 0.72 | ALDH1A1 (0.55) | PKMALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL15208411 | 0.71 | ALDH1A1 (0.48) | PKMALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL20985953 | 0.70 | PKM (0.57) | PKMALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL2293425 | 0.70 | ALDH1A1 (0.53) | PKMALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL5300707 | 0.70 | ALDH1A1 (0.53) | PKMALDH1A1HPGDKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003806-B2 | Integrin antagonists useful as anticancer agents | OSI Pharmaceuticals, LLC (US) | 2011-08-23 | — | — | US | disclosed |