SCHEMBL22929946

SCHEMBL22929946

c1ccc2c(c1)-c1ccc(-n3c4ccccc4c4ccccc43)cc1-c1ccccc1-c1nccnc1-2

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.43
ATM Q13315 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ALDH1A1 P00352 3/20 0.40
DUSP3 P51452 1/20 0.33
PTPRC P08575 2/20 0.32
CTSL P07711 1/20 0.32
CTSS P25774 1/20 0.32
PTPN13 Q12923 1/20 0.32
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
MAPK13 O15264 1/20 0.30
MAPK12 P53778 1/20 0.30
MAPK11 Q15759 1/20 0.30
MAPK14 Q16539 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22930027 0.91 KDM4E (0.41) KDM4EATML3MBTL1ALDH1A1DUSP3
SCHEMBL22929904 0.89 KDM4E (0.42) KDM4EATML3MBTL1ALDH1A1DUSP3
SCHEMBL17947698 0.87 L3MBTL1 (0.56) KDM4EATML3MBTL1ALDH1A1DUSP3
SCHEMBL26519426 0.87 L3MBTL1 (0.56) KDM4EATML3MBTL1ALDH1A1DUSP3
SCHEMBL18252520 0.87 L3MBTL1 (0.56) KDM4EATML3MBTL1ALDH1A1DUSP3
SCHEMBL22929920 0.85 KDM4E (0.39) KDM4EATML3MBTL1ALDH1A1DUSP3
SCHEMBL22036886 0.85 KDM4E (0.39) KDM4EATML3MBTL1ALDH1A1
SCHEMBL18381848 0.85 KDM4E (0.54) KDM4EATML3MBTL1ALDH1A1DUSP3
SCHEMBL14996011 0.85 KDM4E (0.58) KDM4EATML3MBTL1ALDH1A1DUSP3
SCHEMBL20062661 0.82 KDM4E (0.50) KDM4EATML3MBTL1ALDH1A1DUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10910577-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10910577-B2 Organic electroluminescent materials and devices CACNA2D2, ORC3, ANO2 KDM4E 1899/4885ATM 4018/4885L3MBTL1 1530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.