SCHEMBL22929944

SCHEMBL22929944

c1ccc2c(c1)-c1ccc(-n3c4ccccc4c4ccccc43)cc1-c1ccccc1-c1ncncc1-2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.38
KDM4E B2RXH2 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KMT2A Q03164 6/20 0.35
MEN1 O00255 5/20 0.35
CYP1A2 P05177 4/20 0.35
CYP2C19 P33261 3/20 0.35
CYP3A4 P08684 3/20 0.35
USP2 O75604 3/20 0.35
TSHR P16473 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
HBB P68871 1/20 0.35
NCOA1 Q15788 1/20 0.34
NCOA3 Q9Y6Q9 1/20 0.34
ALDH1A1 P00352 2/20 0.33
CYP2C9 P11712 2/20 0.33
DUSP3 P51452 1/20 0.33
CYP17A1 P05093 3/20 0.32
MAPK9 P45984 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22036885 0.87 CYP1A2 (0.38) ATMKDM4EL3MBTL1KMT2AMEN1
SCHEMBL22929969 0.84 ATM (0.35) ATMKDM4EL3MBTL1KMT2AMEN1
SCHEMBL22930027 0.82 KDM4E (0.41) ATMKDM4EL3MBTL1KMT2AMEN1
SCHEMBL22929946 0.81 KDM4E (0.43) ATMKDM4EL3MBTL1ALDH1A1DUSP3
SCHEMBL18252520 0.81 L3MBTL1 (0.56) ATMKDM4EL3MBTL1CYP1A2CYP2C19
SCHEMBL26519426 0.81 L3MBTL1 (0.56) ATMKDM4EL3MBTL1CYP1A2CYP2C19
SCHEMBL17947698 0.81 L3MBTL1 (0.56) ATMKDM4EL3MBTL1CYP1A2CYP2C19
SCHEMBL17991273 0.80 MEN1 (0.31) ATMKDM4EL3MBTL1KMT2AMEN1
SCHEMBL17991230 0.80 MEN1 (0.31) ATMKDM4EL3MBTL1KMT2AMEN1
SCHEMBL21264568 0.79 ATM (0.34) ATMKMT2AMEN1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10910577-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10910577-B2 Organic electroluminescent materials and devices CACNA2D2, ORC3, ANO2 ATM 4018/4885KDM4E 1899/4885L3MBTL1 1530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.