Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18732428 | 0.88 | KDM4E (0.32) | PDK2KDM4EALDH1A1HPGDGAA | |
| SCHEMBL22930618 | 0.87 | PDK2 (0.34) | PDK2KDM4EALDH1A1HPGDGAA | |
| SCHEMBL22930708 | 0.87 | KDM4E (0.35) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL22930616 | 0.85 | ALOX5 (0.39) | PDK2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL18731818 | 0.85 | AHR (0.37) | PDK2 | |
| SCHEMBL19299468 | 0.84 | KDM4E (0.35) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL17879492 | 0.84 | KDM4E (0.37) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL21742871 | 0.82 | PDK2 (0.38) | PDK2KDM4EALDH1A1HPGDGAA | |
| SCHEMBL21742875 | 0.82 | PDK2 (0.38) | PDK2KDM4EALDH1A1HPGDGAA | |
| SCHEMBL22930689 | 0.81 | AHR (0.41) | PDK2KDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10910567-B2 | Double spiro-type compound and organic light emitting diode comprising same | LG CHEM, LTD. | 2021-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10910567-B2 | Double spiro-type compound and organic light emitting diode comprising same | NR2E3, ALDH1A2, CRY1 | PDK2 560/4885KDM4E 2977/4885ALDH1A1 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.