Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889645 | 0.92 | TSHR (0.55) | PDE2ATSHRHPGDLMNATYR | |
| SCHEMBL17923896 | 0.86 | TSHR (0.61) | TSHRESR1ESR2HPGDCYP3A4 | |
| SCHEMBL24390273 | 0.84 | KIF11 (0.56) | PDE2ATSHRHPGDLMNATYR | |
| SCHEMBL1706121 | 0.83 | PDE2A (0.62) | PDE2ATSHRESR1ESR2HPGD | |
| SCHEMBL11553859 | 0.80 | PDE2A (0.54) | PDE2ATSHRESR1ESR2HPGD | |
| SCHEMBL424728 | 0.76 | TSHR (0.73) | TSHRHPGDLMNATYRHSD17B10 | |
| SCHEMBL18531361 | 0.76 | ESR1 (0.65) | TSHRESR1ESR2HPGDCYP3A4 | |
| SCHEMBL24522303 | 0.76 | TSHR (0.83) | TSHRESR1ESR2HPGDCYP3A4 | |
| SCHEMBL17164814 | 0.75 | PDE2A (0.54) | PDE2ANPC1RAB9AKDM4EKIF11 | |
| SCHEMBL22931120 | 0.74 | TSHR (0.48) | TSHRESR1ESR2HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3771723-A1 | ADDITIVE MANUFACTURING ARTICLE AND METHOD | SHPP Global Technologies B.V. (NL) | 2021-02-03 | — | — | EP | disclosed |