Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19910554 | 0.83 | FAAH (0.41) | FAAHMGLLALOX15SMN1; SMN2CYP1A2 | |
| SCHEMBL13533089 | 0.81 | FAAH (0.42) | FAAHMGLLALOX15CYP1A2CYP3A4 | |
| SCHEMBL22400023 | 0.78 | GSK3B (0.40) | FAAHMGLLALOX15SMN1; SMN2CYP1A2 | |
| SCHEMBL22531938 | 0.72 | BCHE (0.43) | FAAHMGLLALOX15HPGDTSHR | |
| SCHEMBL29471954 | 0.72 | BCHE (0.43) | FAAHMGLLALOX15HPGDTSHR | |
| SCHEMBL19755649 | 0.72 | SMN1; SMN2 (0.47) | FAAHMGLLALOX15SMN1; SMN2CYP1A2 | |
| SCHEMBL19755624 | 0.70 | FAAH (0.34) | FAAHMGLLALOX15CYP1A2CYP3A4 | |
| SCHEMBL20148797 | 0.70 | FAAH (0.41) | FAAHMGLLALOX15CYP1A2CYP3A4 | |
| SCHEMBL23316701 | 0.69 | GABRA1 (0.36) | FAAHMGLLCYP1A2CYP3A4HPGD | |
| SCHEMBL21216432 | 0.69 | CREBBP (0.37) | FAAHMGLLCYP1A2CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11584748-B2 | Spirocyclic compounds | C4 THERAPEUTICS, INC. (US) | 2023-02-21 | — | — | US | disclosed |
| US-20210032245-A1 | SPIROCYCLIC COMPOUNDS | C4 THERAPEUTICS, INC. (US) | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210032245-A1 | SPIROCYCLIC COMPOUNDS | CRBN, RBX1, XIAP | FAAH 4752/4885MGLL 4397/4885ALOX15 4526/4885 |
| US-11584748-B2 | Spirocyclic compounds | CRBN, RBX1, XIAP | FAAH 4752/4885MGLL 4397/4885ALOX15 4526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.