Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.33 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.33 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29707205 | 1.00 | HTT (0.39) | HTTNPSR1KDM4EMEN1MAPT | |
| SCHEMBL198146 | 0.80 | GABRA1 (0.42) | HTTNPSR1KDM4EMEN1MAPT | |
| SCHEMBL15003248 | 0.80 | CYP2C19 (0.36) | HTTNPSR1CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL17594504 | 0.80 | CYP2C19 (0.36) | HTTNPSR1CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL28928342 | 0.78 | CYP2C19 (0.35) | HTTNPSR1CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL9994766 | 0.78 | ALDH1A1 (0.48) | HTTNPSR1KDM4EMEN1MAPT | |
| SCHEMBL17594925 | 0.74 | POLB (0.44) | HTTNPSR1KDM4EMEN1MAPT | |
| SCHEMBL13529284 | 0.73 | CYP19A1 (0.33) | — | |
| SCHEMBL2292932 | 0.73 | HSPA5 (0.37) | HSPA5 | |
| SCHEMBL29516681 | 0.72 | CYP2C19 (0.59) | HTTNPSR1CYP2C19CYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805068-B | Preparation method of chiral alpha-hydroxy-beta-keto ester compound | 南京工业大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-113549062-B | Chiral quaternary ammonium salt phase transfer catalyst with high steric hindrance derived from cinchona alkaloid and synthesis method thereof | 南京工业大学 | 2022-08-09 | — | — | CN | disclosed |
| CN-114805068-A | Preparation method of chiral alpha-hydroxy-beta-keto ester compound | 南京工业大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-113549062-A | Chiral quaternary ammonium salt phase transfer catalyst with high steric hindrance derived from cinchona alkaloid and synthesis method thereof | 南京工业大学 | 2021-10-26 | — | — | CN | disclosed |
| EP-2149545-B1 | METHOD FOR PRODUCING BENZALDEHYDE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2016-10-05 | — | — | EP | disclosed |
| WO-2016039691-A1 | CATALYSTS FOR MAKING CHIRAL HETEROCYCLIC SULFOXIDES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-03-17 | — | — | WO | disclosed |
| US-7994367-B2 | Method for producing benzaldehyde compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-09 | — | — | US | disclosed |
| US-20100210879-A1 | METHOD FOR PRODUCING BENZALDEHYDE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-08-19 | — | — | US | disclosed |
| EP-2149545-A1 | METHOD FOR PRODUCING BENZALDEHYDE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2010-02-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210879-A1 | METHOD FOR PRODUCING BENZALDEHYDE COMPOUND | NQO1, C9, TRPA1 | HTT 1687/4885NPSR1 3260/4885KDM4E 1499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.