Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 14/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25959700 | 0.91 | ALOX15 (0.64) | ALOX15LMNANPC1RAB9AMAPT | |
| SCHEMBL25959734 | 0.88 | ALOX15 (0.48) | ALOX15NPC1RAB9AMAPTNPSR1 | |
| SCHEMBL25961136 | 0.88 | NPC1 (0.57) | ALOX15LMNANPC1RAB9AMAPT | |
| SCHEMBL25958304 | 0.87 | POLB (0.48) | ALOX15LMNANPC1RAB9AMAPT | |
| SCHEMBL22939286 | 0.86 | ALOX15 (0.57) | ALOX15LMNAMAPTNPSR1 | |
| SCHEMBL22257182 | 0.85 | ALOX15 (0.57) | ALOX15LMNANPC1RAB9A | |
| SCHEMBL22256818 | 0.84 | ALOX15 (0.53) | ALOX15LMNANPC1RAB9AMAPT | |
| SCHEMBL22939775 | 0.83 | ALOX15 (0.57) | ALOX15LMNAMAPTNPSR1 | |
| SCHEMBL25959732 | 0.82 | ALOX15 (0.56) | ALOX15LMNANPC1RAB9A | |
| SCHEMBL22939768 | 0.81 | ALOX15 (0.58) | ALOX15LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248752-A1 | PRODRUGS OF ALOX-15 INHIBITORS AND METHODS OF USING THE SAME | EMPIRICO INC. | 2023-08-10 | — | — | US | disclosed |
| US-11666588-B2 | Prodrugs of ALOX-15 inhibitors and methods of using the same | EMPIRICO INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-11116778-B2 | Prodrugs of ALOX-15 inhibitors and methods of using the same | EMPIRICO INC. (US) | 2021-09-14 | — | — | US | disclosed |
| US-20210030772-A1 | PRODRUGS OF ALOX-15 INHIBITORS AND METHODS OF USING THE SAME | EMPIRICO INC. | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230248752-A1 | PRODRUGS OF ALOX-15 INHIBITORS AND METHODS OF USING THE SAME | ALOX15, ALOX5, ALOX15B | ALOX15 1/4885LMNA 2806/4885NPC1 2279/4885 |
| US-20210030772-A1 | PRODRUGS OF ALOX-15 INHIBITORS AND METHODS OF USING THE SAME | ALOX15, ALOX5, ALOX15B | ALOX15 1/4885LMNA 2806/4885NPC1 2279/4885 |
| US-11666588-B2 | Prodrugs of ALOX-15 inhibitors and methods of using the same | ALOX15, ALOX5, ALOX15B | ALOX15 1/4885LMNA 2806/4885NPC1 2279/4885 |
| US-11116778-B2 | Prodrugs of ALOX-15 inhibitors and methods of using the same | ALOX15, ALOX5, ALOX15B | ALOX15 1/4885LMNA 2806/4885NPC1 2279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.