Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 7/20 | 0.46 |
| ▸ | CA1 | P00915 | 7/20 | 0.46 |
| ▸ | CA2 | P00918 | 7/20 | 0.46 |
| ▸ | CA9 | Q16790 | 7/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30945310 | 1.00 | TDP1 (0.49) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL9331881 | 1.00 | TDP1 (0.49) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL13788602 | 1.00 | TDP1 (0.49) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL2805155 | 1.00 | TDP1 (0.49) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL450913 | 1.00 | TDP1 (0.49) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL23728804 | 1.00 | TDP1 (0.49) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL21113607 | 1.00 | TDP1 (0.49) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL22515370 | 1.00 | TDP1 (0.49) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL22939675 | 1.00 | TDP1 (0.49) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL30062304 | 1.00 | TDP1 (0.49) | TDP1MAOAMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11975072-B2 | Pyropheophorbide conjugate and use thereof in the treatment of cancer and as a fluorescent marker | UNIVERSITE DE LORRAINE (FR) | 2024-05-07 | — | — | US | claimed |
| CN-115572320-B | Prostate cancer molecular probe and preparation method and application thereof | 中南大学湘雅医院 | 2023-09-12 | — | — | CN | claimed |
| CN-114957346-B | Antibody coupling agent and preparation method and application thereof | 中山大学 | 2023-08-25 | — | — | CN | claimed |
| CN-116396295-A | Synthesis method of PLK1 degradation agent based on PROTAC | 合肥工业大学 | 2023-07-07 | — | — | CN | claimed |
| CN-115572320-A | Prostate cancer molecular probe and preparation method and application thereof | 中南大学湘雅医院 | 2023-01-06 | — | — | CN | claimed |
| US-20220378914-A1 | PYROPHEOPHORBIDE CONJUGATE AND USE THEREOF IN THE TREATMENT OF CANCER AND AS A FLUORESCENT MARKER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2022-12-01 | — | — | US | claimed |
| CN-114957346-A | Antibody coupling agent and preparation method and application thereof | 中山大学 | 2022-08-30 | — | — | CN | claimed |
| EP-3655407-B1 | PYROPHEOPHORBID-KONJUGAT UND DESSEN VERWENDUNG ZUR BEHANDLUNG VON KREBS UND ALS FLUORESZIERENDEN MARKER. | INST NAT SANTE RECH MED (FR) | 2021-08-04 | — | — | EP | claimed |
| US-20190352625-A1 | MUTANTS OF COCAINE ESTERASE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2019-11-21 | — | — | US | claimed |
| US-10160960-B2 | Mutants of cocaine esterase | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2018-12-25 | — | — | US | claimed |
| WO-2015021187-A1 | MUTANTS OF COCAINE ESTERASE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-02-12 | — | — | WO | claimed |
| WO-2014121819-A1 | FOLATE FUNCTIONALIZED NANODIAMOND PARTICLES, METHOD FOR ITS PREPARATION AND THEIR USE | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2014-08-14 | — | — | WO | claimed |
| US-8735439-B2 | Chlorin e6-folic acid conjugate, preparation method thereof, and a pharmaceutical composition for the treatment of cancer comprising the same | DIATECH KOREA CO., LTD. (KR) | 2014-05-27 | — | — | US | claimed |
| EP-2431366-A1 | NEW CHLORINE E6-FOLIC ACID CONJUGATED COMPOUND, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR TREATMENT OF CANCER | Diatech Korea Co., Ltd. (KR) | 2012-03-21 | — | — | EP | claimed |
| US-20120059018-A1 | NOVEL CHLORIN E6-FOLIC ACID CONJUGATE, PREPARATION METHOD THEREOF, AND A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF CANCER COMPRISING THE SAME | DIATECH KOREA CO., LTD. (KR) | 2012-03-08 | — | — | US | claimed |
| US-20100105149-A1 | FLUORESCENT DYE-LABELED GLUCOSE BIOPROBE, SYNTHESIS METHOD AND USAGE THEREOF | SNU R&DB FOUNDATION (KR) | 2010-04-29 | — | — | US | claimed |
| WO-2008117918-A1 | FLUORESCENT DYE-LABELED GLUCOSE BIOPROBE, SYNTHESIS METHOD AND USAGE THEREOF | SNU R&DB FOUNDATION (KR) | 2008-10-02 | — | — | WO | claimed |
| US-20030069445-A1 | Biological reagents and methods for determining the mechanism in the generation of beta-amyloid peptide | AUDIA JAMES E (US) | 2003-04-10 | — | — | US | claimed |
| EP-1131634-A2 | DETERMINING THE MECHANISM OF BETA-AMYLOID PEPTIDE GENERATION | Elan Pharmaceuticals, Inc. (US) | 2001-09-12 | — | — | EP | claimed |
| WO-2000019210-A2 | DETERMINING THE MECHANISM OF BETA-AMYLOID PEPTIDE GENERATION | ELAN PHARMACEUTICALS, INC. (US) | 2000-04-06 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059018-A1 | NOVEL CHLORIN E6-FOLIC ACID CONJUGATE, PREPARATION METHOD THEREOF, AND A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF CANCER COMPRISING THE SAME | FOLR1, FOLR2, DHFR | TDP1 3593/4885MAOA 685/4885MAOB 602/4885 |
| US-11975072-B2 | Pyropheophorbide conjugate and use thereof in the treatment of cancer and as a fluorescent marker | FOLH1, SLC46A1, PPOX | TDP1 1980/4885MAOA 1549/4885MAOB 800/4885 |
| US-20220378914-A1 | PYROPHEOPHORBIDE CONJUGATE AND USE THEREOF IN THE TREATMENT OF CANCER AND AS A FLUORESCENT MARKER | FOLH1, SLC46A1, PPOX | TDP1 1980/4885MAOA 1549/4885MAOB 800/4885 |
| US-20100105149-A1 | FLUORESCENT DYE-LABELED GLUCOSE BIOPROBE, SYNTHESIS METHOD AND USAGE THEREOF | GALE, OGA, GNE | TDP1 3077/4885MAOA 1633/4885MAOB 1354/4885 |
| US-20030069445-A1 | Biological reagents and methods for determining the mechanism in the generation of beta-amyloid peptide | APP, IAPP, BACE1 | TDP1 910/4885MAOA 364/4885MAOB 265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.