Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.50 |
| ▸ | ALK | Q9UM73 | 12/20 | 0.49 |
| ▸ | INSR | P06213 | 9/20 | 0.49 |
| ▸ | IGF1R | P08069 | 9/20 | 0.49 |
| ▸ | EGFR | P00533 | 7/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22942226 | 0.92 | EGFR (0.56) | ALKINSRIGF1REGFR | |
| SCHEMBL22942153 | 0.89 | EGFR (0.59) | LRRK2ALKINSRIGF1REGFR | |
| SCHEMBL22942156 | 0.88 | INSR (0.61) | LRRK2ALKINSRIGF1REGFR | |
| SCHEMBL22942225 | 0.80 | EGFR (0.67) | ALKINSRIGF1REGFR | |
| SCHEMBL22942149 | 0.80 | INSR (0.69) | LRRK2ALKINSRIGF1REGFR | |
| SCHEMBL22942870 | 0.80 | EGFR (0.66) | ALKINSRIGF1REGFR | |
| SCHEMBL29559850 | 0.80 | EGFR (0.66) | ALKINSRIGF1REGFR | |
| SCHEMBL29560293 | 0.78 | ALK (0.58) | ALKINSRIGF1REGFR | |
| SCHEMBL29559735 | 0.78 | EGFR (0.65) | EGFR | |
| SCHEMBL22943345 | 0.78 | EGFR (0.56) | ALKINSRIGF1REGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018003-A1 | EGFR INHIBITOR, COMPOSITION, AND PREPARATION METHOD THEREFOR | 贝达药业股份有限公司 | 2021-02-04 | — | — | WO | disclosed |