SCHEMBL22944280

SCHEMBL22944280

CCc1cnc(Cl)c(Cl)c1Cl

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.38
NOS1 P29475 1/20 0.38
NOS2 P35228 1/20 0.38
PDXK O00764 1/20 0.36
ALDH1A1 P00352 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
CTRC Q99895 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL29000598 0.90 GABRP (0.36) NOS3NOS1NOS2PDXKALDH1A1
SCHEMBL24982634 0.80 NOS3 (0.42) NOS3NOS1NOS2PDXKALDH1A1
SCHEMBL22944344 0.80 NOS3 (0.34) NOS3NOS1NOS2PDXKALDH1A1
SCHEMBL10483967 0.78 PDXK (0.38) PDXK
SCHEMBL21919500 0.77 NOS3 (0.44) NOS3NOS1NOS2
SCHEMBL27980296 0.76 POLB (0.41) NOS3NOS1NOS2PDXKALDH1A1
SCHEMBL29047829 0.74 NOS3 (0.41) NOS3NOS1NOS2PDXKALDH1A1
SCHEMBL29456615 0.70 SMN1; SMN2 (0.36) ALDH1A1
SCHEMBL24653595 0.70
SCHEMBL22859671 0.70 NOS3 (0.37) NOS3NOS1NOS2PDXKALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021018226-A1 HETEROCYCLIC COMPOUND AND APPLICATION THEREOF 深圳微芯生物科技股份有限公司 2021-02-04 WO disclosed