Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 7/20 | 0.79 |
| ▸ | LMNA | P02545 | 3/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.79 |
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HSPA9 | P38646 | 3/20 | 0.51 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.51 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16369642 | 0.88 | FFAR2 (1.00) | FFAR2LMNAMEN1KMT2ATSHR | |
| SCHEMBL16369644 | 0.88 | FFAR2 (1.00) | FFAR2LMNAMEN1KMT2ATSHR | |
| SCHEMBL1107000 | 0.76 | ADORA2A (0.68) | FFAR2LMNAMEN1KMT2ATSHR | |
| SCHEMBL8246090 | 0.75 | LMNA (0.59) | FFAR2LMNAMEN1KMT2ATSHR | |
| SCHEMBL1565491 | 0.74 | NPC1 (0.54) | FFAR2LMNAMEN1KMT2ATSHR | |
| SCHEMBL1564845 | 0.74 | LMNA (0.69) | FFAR2LMNAMEN1KMT2ANPC1 | |
| SCHEMBL23804604 | 0.74 | LMNA (0.59) | FFAR2LMNAMEN1KMT2ATSHR | |
| SCHEMBL7876872 | 0.74 | LMNA (0.59) | FFAR2LMNAMEN1KMT2ATSHR | |
| Bromide SCHEMBL11310364 | 0.74 | LMNA (0.58) | FFAR2LMNAMEN1KMT2ATSHR | |
| SCHEMBL3223685 | 0.74 | RAB9A (1.00) | LMNAMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018786-A1 | USE OF FFAR2 AGONISTS FOR THE TREATMENT OF BACTERIAL SUPERINFECTIONS POST-VIRAL INFECTION | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2021-02-04 | — | — | WO | disclosed |