SCHEMBL22945154

SCHEMBL22945154

c1ccc2c3c(ccc2c1)-c1cccc2cccc(c12)N3c1ccc2cc(-c3nc(-c4ccncc4)c4ccccc4n3)ccc2c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.35
KDM4E B2RXH2 6/20 0.35
MEN1 O00255 5/20 0.35
KMT2A Q03164 5/20 0.35
MAPK9 P45984 2/20 0.35
MAPK10 P53779 2/20 0.35
ATM Q13315 1/20 0.35
MAPK8 P45983 1/20 0.35
USP2 O75604 1/20 0.34
TSHR P16473 1/20 0.34
HPGD P15428 5/20 0.34
MAPT P10636 7/20 0.34
LMNA P02545 5/20 0.34
ALDH1A1 P00352 3/20 0.34
MAPK1 P28482 3/20 0.33
ABCG2 Q9UNQ0 2/20 0.32
TP53 P04637 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2D6 P10635 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21515473 0.91 PDE6D (0.38) PDE6DKDM4EMEN1KMT2AMAPK9
SCHEMBL22945345 0.89 PDE6D (0.36) PDE6DKDM4EMEN1KMT2AMAPK9
SCHEMBL22946111 0.87
SCHEMBL22945040 0.85 MAPK9 (0.32) PDE6DKDM4EKMT2AMAPK9MAPK10
SCHEMBL22945155 0.84 HPGD (0.39) KDM4EMEN1KMT2AUSP2TSHR
SCHEMBL26736984 0.83 ALDH1A1 (0.41) PDE6DKDM4EMEN1KMT2AATM
SCHEMBL22945590 0.82 PDE6D (0.33) PDE6D
SCHEMBL22945146 0.81 PDE6D (0.33) PDE6DMEN1KMT2AATMTP53
SCHEMBL26736991 0.80 TP53 (0.35) PDE6DKDM4EMEN1KMT2AATM
SCHEMBL22945452 0.79 PDE6D (0.33) PDE6DKDM4EMEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2021-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME DRD1, DRD3, DRD2 PDE6D 342/4885KDM4E 1857/4885MEN1 1827/4885
US-11812658-B2 Compound and organic light emitting diode comprising same DRD1, DRD3, DRD2 PDE6D 342/4885KDM4E 1857/4885MEN1 1827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.