SCHEMBL22945146

SCHEMBL22945146

c1cc(-c2nc(-c3ccc(-c4cccc5cccnc45)cc3)c3ccccc3n2)c2cc(N3c4c(ccc5ccccc45)-c4cccc5cccc3c45)ccc2c1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.33
PSMD14 O00487 1/20 0.32
TP53 P04637 1/20 0.32
POLB P06746 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31
PDE10A Q9Y233 1/20 0.31
FABP1 P07148 1/20 0.31
ENPP1 P22413 1/20 0.31
TOP2A P11388 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21515295 0.89 PDE6D (0.34) PDE6DPSMD14TP53POLBMMP2
SCHEMBL22945145 0.87 PDE6D (0.38) PDE6DPSMD14TP53POLBMMP2
SCHEMBL22944865 0.86 ALDH1A1 (0.37) PDE6DPOLBMMP9MEN1KMT2A
SCHEMBL26737063 0.86 KDM4E (0.30) POLBMEN1KMT2A
SCHEMBL22945467 0.83 MEN1 (0.34) PDE6DPOLBMMP9MEN1KMT2A
SCHEMBL22945685 0.82 MMP9 (0.33) PDE6DMMP9MEN1KMT2AATM
SCHEMBL22945154 0.81 PDE6D (0.35) PDE6DTP53POLBMEN1KMT2A
SCHEMBL22946111 0.81
SCHEMBL22945147 0.79 METAP1 (0.38) PDE6DTP53POLBMEN1KMT2A
SCHEMBL21515476 0.78 ALDH1A1 (0.38) PDE6DPOLBMMP9KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2021-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME DRD1, DRD3, DRD2 PDE6D 342/4885PSMD14 987/4885TP53 4333/4885
US-11812658-B2 Compound and organic light emitting diode comprising same DRD1, DRD3, DRD2 PDE6D 342/4885PSMD14 987/4885TP53 4333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.