SCHEMBL22945492

SCHEMBL22945492

c1ccc(-c2nc(N3c4ccccc4-c4cccc5cccc3c45)nc3c2sc2ccccc23)cc1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.37
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
MAPK1 P28482 1/20 0.37
RECQL P46063 1/20 0.37
MMP14 P50281 1/20 0.37
KMT2A Q03164 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
LIMK1 P53667 1/20 0.33
TNKS O95271 2/20 0.31
TNKS2 Q9H2K2 2/20 0.31
PIM1 P11309 1/20 0.31
PIM2 Q9P1W9 1/20 0.31
HRH4 Q9H3N8 1/20 0.31
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22945494 0.98 PDE6D (0.40) PDE6DMAPTMEN1LMNAMAPK1
SCHEMBL22944980 0.93 PDE6D (0.35) PDE6DMAPTMEN1LMNAMAPK1
SCHEMBL22944957 0.93 KDM4E (0.33) PDE6DMAPTMEN1LMNAMAPK1
SCHEMBL22944880 0.92 MAPK1 (0.34) PDE6DMAPTMEN1LMNAMAPK1
SCHEMBL22944969 0.90 POLB (0.32) PDE6DMAPTMAPK1L3MBTL1LIMK1
SCHEMBL22944973 0.90 TGFBR1 (0.35) PDE6DMAPTMEN1MAPK1KMT2A
SCHEMBL22944975 0.90 PDE6D (0.33) PDE6DTNKSTNKS2ALOX5
SCHEMBL22944877 0.90 PDE6D (0.38) PDE6DMAPTMEN1LMNAMAPK1
SCHEMBL22945493 0.90 S1PR5 (0.33) PDE6DMAPK1TNKSTNKS2ALOX5
SCHEMBL22944767 0.90 MEN1 (0.36) PDE6DMAPTMEN1LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2021-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME DRD1, DRD3, DRD2 PDE6D 342/4885MAPT 2771/4885MEN1 1827/4885
US-11812658-B2 Compound and organic light emitting diode comprising same DRD1, DRD3, DRD2 PDE6D 342/4885MAPT 2771/4885MEN1 1827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.