SCHEMBL22944975

SCHEMBL22944975

c1ccc2c(c1)-c1cccc3cccc(c13)N2c1nc(-c2ccc(-c3ccc4ccccc4c3)cc2)c2sc3ccccc3c2n1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.33
S1PR4 O95977 3/20 0.32
S1PR5 Q9H228 3/20 0.32
ALOX5 P09917 1/20 0.31
TNKS O95271 1/20 0.30
TNKS2 Q9H2K2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22945493 0.96 S1PR5 (0.33) PDE6DS1PR4S1PR5ALOX5TNKS
SCHEMBL22945762 0.94 PDE6D (0.32) PDE6DS1PR4S1PR5ALOX5TNKS
SCHEMBL22945494 0.92 PDE6D (0.40) PDE6DALOX5TNKSTNKS2
SCHEMBL22945612 0.92 PDE6D (0.32) PDE6DS1PR4S1PR5
SCHEMBL22945279 0.91 PDE6D (0.31) PDE6DS1PR4S1PR5
SCHEMBL22944876 0.90 ALDH1A1 (0.32) PDE6DS1PR4S1PR5ALOX5TNKS
SCHEMBL22945492 0.90 PDE6D (0.37) PDE6DALOX5TNKSTNKS2
SCHEMBL22944877 0.89 PDE6D (0.38) PDE6DALOX5TNKSTNKS2
SCHEMBL22945911 0.87 ALOX5 (0.34) PDE6DALOX5TNKSTNKS2
SCHEMBL22944957 0.87 KDM4E (0.33) PDE6D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2021-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME DRD1, DRD3, DRD2 PDE6D 342/4885S1PR4 3775/4885S1PR5 3443/4885
US-11812658-B2 Compound and organic light emitting diode comprising same DRD1, DRD3, DRD2 PDE6D 342/4885S1PR4 3775/4885S1PR5 3443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.