Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | BCL9 | O00512 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | PTAFR | P25105 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22945960 | 0.84 | POLB (0.36) | HTR2APIK3CDBCL9CTNNB1PTAFR | |
| SCHEMBL21275892 | 0.77 | ACHE (0.41) | THRBRORCPOLBGAAGFER | |
| SCHEMBL16133976 | 0.75 | PDE3B (0.33) | HTR2ABCL9CTNNB1GAALPAR1 | |
| SCHEMBL24371608 | 0.74 | GAA (0.41) | THRBRORCPOLBGAAGFER | |
| SCHEMBL15713203 | 0.72 | HDAC4 (0.42) | BCL9CTNNB1 | |
| SCHEMBL28706178 | 0.71 | TACR1 (0.37) | POLBACHE | |
| SCHEMBL16134106 | 0.70 | POLB (0.35) | HTR2APOLBGAAGFERPDE3B | |
| SCHEMBL16071630 | 0.69 | HTR1A (0.35) | HTR2ABCL9CTNNB1PTAFRGAA | |
| SCHEMBL20259973 | 0.69 | POLB (0.40) | HTR2ATHRBRORCPOLBGAA | |
| SCHEMBL16059420 | 0.68 | GAA (0.40) | HTR2ABCL9CTNNB1GAACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4008405-A1 | UREA COMPOUND FOR ANTAGONIZING LPA1 RECEPTOR | Taisho Pharmaceutical Co., Ltd. (JP) | 2022-06-08 | — | — | EP | disclosed |
| WO-2021020429-A1 | UREA COMPOUND FOR ANTAGONIZING LPA1 RECEPTOR | 大正製薬株式会社 | 2021-02-04 | — | — | WO | disclosed |