SCHEMBL22945965

SCHEMBL22945965

CCOc1cc(C(C)C)cc(C)c1CO

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 8/20 0.40
BCHE P06276 6/20 0.40
TAS1R3 Q7RTX0 2/20 0.35
TAS1R1 Q7RTX1 2/20 0.35
GABRA1 P14867 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
ADRA2A P08913 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
ADRA1D P25100 1/20 0.35
HTR1D P28221 1/20 0.35
HTR1B P28222 1/20 0.35
ADRA1A P35348 1/20 0.35
ADRA1B P35368 1/20 0.35
KMT2A Q03164 2/20 0.34
MAPT P10636 2/20 0.34
MEN1 O00255 1/20 0.34
TSHR P16473 1/20 0.33
ALDH1A1 P00352 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7979673 0.80 ADRA2A (0.43) ACHEBCHEGABRA1GABRG2GABRB3
SCHEMBL22946271 0.79 ACHE (0.41) ACHEBCHETAS1R3TAS1R1KMT2A
SCHEMBL22945628 0.76 ACHE (0.41) ACHEBCHETAS1R3TAS1R1KMT2A
SCHEMBL22946243 0.74 BCHE (0.45) ACHEBCHETAS1R3TAS1R1KMT2A
SCHEMBL9945999 0.72 POLB (0.40) ACHEBCHEGABRA1ADRA2AADRA2B
SCHEMBL24488941 0.72 ACHE (0.38) ACHEBCHEGABRA1KMT2AMAPT
SCHEMBL29654960 0.72 ACHE (0.63) ACHEBCHEKMT2AMAPTMEN1
SCHEMBL356804 0.72 ACHE (0.63) ACHEBCHEKMT2AMAPTMEN1
SCHEMBL11449830 0.72 KMT2A (0.48) ACHEBCHETAS1R3TAS1R1KMT2A
SCHEMBL17084603 0.71 HTR2A (0.44) ACHEBCHEGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021020429-A1 UREA COMPOUND FOR ANTAGONIZING LPA1 RECEPTOR 大正製薬株式会社 2021-02-04 WO disclosed