Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
| ▸ | BCHE | P06276 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22945628 | 0.90 | ACHE (0.41) | ACHEBCHEALDH1A1HTTKMT2A | |
| SCHEMBL19726451 | 0.81 | CRHR1 (0.45) | ACHEBCHEALDH1A1HTTKMT2A | |
| SCHEMBL19726455 | 0.81 | ACHE (0.38) | ACHEBCHEALDH1A1HTTKMT2A | |
| SCHEMBL19726449 | 0.81 | KMT2A (0.41) | ACHEBCHEALDH1A1HTTKMT2A | |
| SCHEMBL22945965 | 0.79 | ACHE (0.40) | ACHEBCHEALDH1A1HTTKMT2A | |
| SCHEMBL9945999 | 0.78 | POLB (0.40) | ACHEBCHEALDH1A1HTTKMT2A | |
| SCHEMBL17084596 | 0.78 | HDAC4 (0.40) | ACHEKMT2ALMNAMEN1 | |
| SCHEMBL22945790 | 0.78 | ACHE (0.34) | ACHEBCHEALDH1A1HTTKMT2A | |
| SCHEMBL356804 | 0.77 | ACHE (0.63) | ACHEBCHEALDH1A1HTTKMT2A | |
| SCHEMBL29654960 | 0.77 | ACHE (0.63) | ACHEBCHEALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021020429-A1 | UREA COMPOUND FOR ANTAGONIZING LPA1 RECEPTOR | 大正製薬株式会社 | 2021-02-04 | — | — | WO | disclosed |