Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.68 |
| ▸ | APEX1 | P27695 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | PPM1B | O75688 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1756841 | 1.00 | POLB (0.68) | POLBAPEX1TDP1PPM1BPTPN1 | |
| SCHEMBL16199052 | 1.00 | POLB (0.68) | POLBAPEX1TDP1PPM1BPTPN1 | |
| SCHEMBL1756845 | 1.00 | POLB (0.68) | POLBAPEX1TDP1PPM1BPTPN1 | |
| SCHEMBL15400303 | 1.00 | POLB (0.68) | POLBAPEX1TDP1PPM1BPTPN1 | |
| SCHEMBL26003315 | 1.00 | POLB (0.68) | POLBAPEX1TDP1PPM1BPTPN1 | |
| SCHEMBL22947120 | 1.00 | POLB (0.68) | POLBAPEX1TDP1PPM1BPTPN1 | |
| SCHEMBL19258989 | 0.92 | POLB (0.57) | POLBAPEX1TDP1PPM1BPTPN1 | |
| SCHEMBL16199396 | 0.92 | POLB (0.57) | POLBAPEX1TDP1PPM1BPTPN1 | |
| SCHEMBL15400698 | 0.92 | POLB (0.57) | POLBAPEX1TDP1PPM1BPTPN1 | |
| SCHEMBL9977663 | 0.92 | POLB (0.57) | POLBAPEX1TDP1PPM1BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339943-A1 | ANTI-INFLUENZA VIRUS PYRIMIDINE DERIVATIVES | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2023-10-26 | — | — | US | disclosed |
| US-20230339943-A1 | ANTI-INFLUENZA VIRUS PYRIMIDINE DERIVATIVES | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2023-10-26 | — | — | US | disclosed |
| US-11725009-B2 | Anti-influenza virus pyrimidine derivative | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2023-08-15 | — | — | US | disclosed |
| US-11725009-B2 | Anti-influenza virus pyrimidine derivative | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2023-08-15 | — | — | US | disclosed |
| US-20220135558-A1 | ANTI-INFLUENZA VIRUS PYRIMIDINE DERIVATIVE | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2022-05-05 | — | — | US | disclosed |
| US-11136319-B2 | Anti-influenza virus pyrimidine derivative | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2021-10-05 | — | — | US | disclosed |
| US-20210032238-A1 | ANTI-INFLUENZA VIRUS PYRIMIDINE DERIVATIVE | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11725009-B2 | Anti-influenza virus pyrimidine derivative | ENTPD5, NUDT15, ITPA | POLB 390/4885APEX1 4108/4885TDP1 395/4885 |
| US-20220135558-A1 | ANTI-INFLUENZA VIRUS PYRIMIDINE DERIVATIVE | ENTPD5, NUDT15, ITPA | POLB 390/4885APEX1 4108/4885TDP1 395/4885 |
| US-20230339943-A1 | ANTI-INFLUENZA VIRUS PYRIMIDINE DERIVATIVES | ENTPD5, NUDT1, ITPA | POLB 296/4885APEX1 3850/4885TDP1 354/4885 |
| US-20210032238-A1 | ANTI-INFLUENZA VIRUS PYRIMIDINE DERIVATIVE | ENTPD5, NUDT15, ITPA | POLB 390/4885APEX1 4108/4885TDP1 395/4885 |
| US-11136319-B2 | Anti-influenza virus pyrimidine derivative | ENTPD5, NUDT15, ITPA | POLB 390/4885APEX1 4108/4885TDP1 395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.