Sugi Predict

Sugi Predict / Targets / NUDT15

NUDT15

Nucleotide triphosphate diphosphatase NUDT15 · Q9NV35 · NUDT15 on Sugi Atlas →

113 patent compounds predicted against NUDT15, 102 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL26434400 SCHEMBL26434400 0.56 1/20
SCHEMBL21313825 SCHEMBL21313825 0.54 1/20
SCHEMBL5324555 SCHEMBL5324555 0.54 1/20
SCHEMBL18315571 SCHEMBL18315571 0.53 1/20
SCHEMBL8534513 SCHEMBL8534513 0.53 1/20
SCHEMBL22216445 SCHEMBL22216445 0.53 1/20
SCHEMBL30226931 SCHEMBL30226931 0.53 1/20
SCHEMBL30329646 SCHEMBL30329646 0.53 1/20
SCHEMBL3039407 SCHEMBL3039407 0.53 1/20
SCHEMBL22216392 SCHEMBL22216392 0.53 1/20
SCHEMBL31428795 SCHEMBL31428795 0.53 1/20
SCHEMBL762616 SCHEMBL762616 0.53 1/20
SCHEMBL2214616 SCHEMBL2214616 0.52 1/20
SCHEMBL3457123 SCHEMBL3457123 0.52 1/20
SCHEMBL29944365 SCHEMBL29944365 0.52 1/20
SCHEMBL5326524 SCHEMBL5326524 0.51 1/20
SCHEMBL3386763 SCHEMBL3386763 0.51 1/20
SCHEMBL30066210 SCHEMBL30066210 0.51 1/20
SCHEMBL106731 SCHEMBL106731 0.50 1/20
SCHEMBL118595 SCHEMBL118595 0.50 1/20

Clinical trials — most relevant to NUDT15 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Safety and Efficacy of BMS-986504 in Unresectable Malignant Peripheral Nerve Sheath Tumor PHASE1/PHASE2NOT_YET_RECRUITING
Nucleoside Therapy in Patients With Telomere Biology Disorders PHASE1RECRUITING
Minimising Adverse Drug Reactions and Verifying Economic Legitimacy in Children (MARVEL-PIC) nanRECRUITING
CoMPaSS-NMD - Computational Models for New Patients Stratification Strategies of HNMD nanENROLLING_BY_INVITATION
A Study of the Interaction Between Tumor Susceptibility Gene Glycine N-methyltransferase (GNMT) and Lung Cancer nanUNKNOWN
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Genetic Analysis of Inherited Urologic Malignant Disorders: Collection of Samples nanCOMPLETED
Gene Analysis of Parkinson's Disease nanCOMPLETED
Study of Constitutional Platelet Disease nanUNKNOWN
Markers and Mechanisms of Macrovascular Disease in IDDM nanCOMPLETED
Exome Sequencing for Atypical Femoral Fractures nanCOMPLETED
Biopsies of Cancer Patients for Tumor Molecular Characterization nanCOMPLETED
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients nanRECRUITING
A Prospective Study of Molecular Detection of Salvageable Early Recurrent Nasopharyngeal Carcinoma After Radiotherapy nanCOMPLETED
Mutations and Phenotypes of Unclassifiable Inherited Bone Marrow Failure Syndromes nanRECRUITING
Quantitative Assessment of the Etiologies of Megalencephaly Associated With a Detectable Tumor Risk nanNOT_YET_RECRUITING
Pathophysiology of Paget's Disease of Bone nanCOMPLETED
Hereditary Nonpolyposis Colorectal Cancer in Taiwan-Related Genetic Study and Clinical Applications nanUNKNOWN
Long-read Genome Sequencing for the Molecular Diagnosis of Dystonia nanRECRUITING
Telomeres Length in Israeli Fibrotic ILD Patients nanENROLLING_BY_INVITATION
Germline Mutations in Pancreatic Adenocarcinoma nanCOMPLETED
Genetic Analysis of Hereditary Disorders of Hearing and Balance nanCOMPLETED
Study of the Genetic and Epigenetic Causes of Recurrent Hydatidiform Moles nanACTIVE_NOT_RECRUITING
Screening for Early Pancreatic Neoplasia (Cancer of the Pancreas Screening or CAPS4 Study) nanCOMPLETED
DNA Adductomics for Colorectal Cancer Investigation nanUNKNOWN
Genetics of Neonatal Encephalopathy and Related Disorders nanRECRUITING
Diagnosis and Phenotype Characterisation Using Genomics in Patients With Inherited Bone Marrow Failure (IBMDx Study) nanRECRUITING
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
Thermogenic Silencer Regulatory Factors in Humans nanACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a NUDT15 binder may also engage these)

ProteinNameSimilarity
Q8BG93 — 0.995 Q8BG93 →
P53370 — 0.979 P53370 →
P0C024 — 0.979 P0C024 →
Q9NZJ9 — 0.978 Q9NZJ9 →
P13420 — 0.977 P13420 →
Q568Q0 — 0.976 Q568Q0 →
Q99P30 — 0.976 Q99P30 →
A0A024RBG1 — 0.975 A0A024RBG1 →
M4I1C6 — 0.975 M4I1C6 →
Q5RAF0 — 0.975 Q5RAF0 →
Q99MY2 — 0.975 Q99MY2 →
Q9SJC4 — 0.974 Q9SJC4 →
Q9JI46 — 0.974 Q9JI46 →
Q566C7 — 0.974 Q566C7 →
Q9DCN1 — 0.973 Q9DCN1 →
Q8R2U6 — 0.973 Q8R2U6 →
Q9SJC6 — 0.973 Q9SJC6 →
Q9SU14 — 0.973 Q9SU14 →
Q8NFP7 — 0.972 Q8NFP7 →
O95989 — 0.972 O95989 →
A2VE79 — 0.972 A2VE79 →
B5XNX5 — 0.972 B5XNX5 →
Q96G61 — 0.972 Q96G61 →
Q94B74 — 0.972 Q94B74 →
Q9CA40 — 0.972 Q9CA40 →
Q4WM52 — 0.971 Q4WM52 →
Q6NPD7 — 0.971 Q6NPD7 →
Q86X67 — 0.971 Q86X67 →
P96590 — 0.971 P96590 →
B7N5L6 — 0.971 B7N5L6 →