Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 14/20 | 0.45 |
| ▸ | LPL | P06858 | 13/20 | 0.45 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22949269 | 0.90 | LIPG (0.55) | LIPGLPLP4HBDGAT1CA1 | |
| SCHEMBL11978736 | 0.85 | LIPG (0.46) | LIPGLPLP4HBPRMT5WDR77 | |
| SCHEMBL31187004 | 0.83 | LIPG (0.46) | LIPGLPLP4HBPRMT5WDR77 | |
| SCHEMBL31757597 | 0.83 | LIPG (0.46) | LIPGLPLP4HBPRMT5WDR77 | |
| SCHEMBL11978734 | 0.83 | LIPG (0.46) | LIPGLPLP4HBPRMT5WDR77 | |
| SCHEMBL22947509 | 0.82 | LIPG (0.38) | LIPGLPL | |
| SCHEMBL22949541 | 0.80 | LIPG (0.51) | LIPGLPLP4HBDGAT1CA1 | |
| SCHEMBL22949401 | 0.80 | LIPG (0.46) | LIPGLPLP4HBPRMT5WDR77 | |
| SCHEMBL31040334 | 0.80 | LIPG (0.46) | LIPGLPLP4HBPRMT5WDR77 | |
| SCHEMBL22947478 | 0.78 | LIPG (0.40) | LIPGLPLP4HBPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210036245-A1 | HETEROAROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210036245-A1 | HETEROAROMATIC COMPOUNDS | ETV6, FES, LEF1 | LIPG 2970/4885LPL 4404/4885P4HB 1426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.