SCHEMBL11978734

SCHEMBL11978734

CC1(C)OB(c2ccc3c(c2)[Si](C)(C)c2ccccc2-3)OC1(C)C

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 14/20 0.46
LPL P06858 13/20 0.46
PRMT5 O14744 1/20 0.37
WDR77 Q9BQA1 1/20 0.37
RORA P35398 1/20 0.35
RORC P51449 1/20 0.35
P4HB P07237 1/20 0.35
ROCK1 Q13464 1/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
CA12 O43570 1/20 0.34
CA3 P07451 1/20 0.34
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34
CA5A P35218 1/20 0.34
CA7 P43166 1/20 0.34
CA14 Q9ULX7 1/20 0.34
CA5B Q9Y2D0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31187004 1.00 LIPG (0.46) LIPGLPLPRMT5WDR77RORA
SCHEMBL31757597 1.00 LIPG (0.46) LIPGLPLPRMT5WDR77RORA
SCHEMBL14816705 0.92 LIPG (0.44) LIPGLPLP4HBCA1CA2
SCHEMBL23868914 0.91 LIPG (0.46) LIPGLPLPRMT5WDR77RORA
SCHEMBL22947506 0.89 LIPG (0.56) LIPGLPLP4HBCA1CA2
SCHEMBL23868765 0.87 LIPG (0.50) LIPGLPLPRMT5WDR77P4HB
SCHEMBL16598114 0.86 LIPG (0.60) LIPGLPLPRMT5WDR77P4HB
SCHEMBL22947447 0.83 LIPG (0.45) LIPGLPLPRMT5WDR77P4HB
SCHEMBL11978736 0.81 LIPG (0.46) LIPGLPLPRMT5WDR77P4HB
SCHEMBL22947602 0.80 LIPG (0.39) LIPGLPLRORARORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210300951-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2021-09-30 US disclosed
US-11056664-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2021-07-06 US disclosed
US-20210036245-A1 HETEROAROMATIC COMPOUNDS MERCK PATENT GMBH (DE) 2021-02-04 US disclosed
US-20170373267-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-12-28 US disclosed
US-20170069856-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-09 US disclosed
US-20170069856-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-09 US disclosed
US-20120206037-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) 2012-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120206037-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME OCIAD1, OCIAD2, OSBPL8 LIPG 114/4885LPL 147/4885PRMT5 3731/4885
US-20170069856-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME OCIAD1, OCIAD2, IDO1 LIPG 2657/4885LPL 1633/4885PRMT5 3805/4885
US-11056664-B2 Organic light-emitting device EML4, L1CAM, OR10J3 LIPG 566/4885LPL 750/4885PRMT5 4222/4885
US-20210300951-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 LIPG 1255/4885LPL 2273/4885PRMT5 4837/4885
US-20210036245-A1 HETEROAROMATIC COMPOUNDS ETV6, FES, LEF1 LIPG 2970/4885LPL 4404/4885PRMT5 1715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.