SCHEMBL2294853

SCHEMBL2294853

O=C(CS(=O)(=O)O)CS(=O)(=O)O.[SrH2]

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACP1 P24666 3/20 0.37
POLB P06746 1/20 0.35
PTGS1 P23219 1/20 0.33
PDE4A P27815 1/20 0.33
CA5A P35218 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
LMNA P02545 1/20 0.33
SLC6A6 P31641 1/20 0.33
CYP2C19 P33261 1/20 0.33
BLM P54132 1/20 0.33
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4968468 0.96 ACP1 (0.38) ACP1POLBPTGS1PDE4ACA5A
SCHEMBL8746852 0.93 ACP1 (0.37) ACP1POLBPTGS1PDE4ACA5A
SCHEMBL5302410 0.83 ACP1 (0.35) ACP1POLBPTGS1PDE4ACA5A
SCHEMBL8539184 0.78
SCHEMBL11452718 0.78
SCHEMBL6049672 0.78
SCHEMBL9309131 0.76 LDHA (0.42) ACP1POLB
SCHEMBL29094022 0.74 CES2 (0.41)
SCHEMBL6547836 0.74 LMNA (0.47) POLBLMNACYP2C19
SCHEMBL9509653 0.74 KDM4E (0.42) ACP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070244191-A1 Strontium salts of sulphonic acids, a process for their preparation and pharmaceutical compositions containing them LES LABORATOIRES SERVIER (FR) 2007-10-18 US claimed
US-7999009-B2 Strontium salts of sulphonic acids, a process for their preparation and pharmaceutical compositions containing them LES LABORATOIRES SERVIER (FR) 2011-08-16 US disclosed
US-20070244191-A1 Strontium salts of sulphonic acids, a process for their preparation and pharmaceutical compositions containing them LES LABORATOIRES SERVIER (FR) 2007-10-18 US disclosed