Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 7/20 | 0.36 |
| ▸ | RAB9A | P51151 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.36 |
| ▸ | RELA | Q04206 | 3/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22947678 | 0.96 | L3MBTL1 (0.39) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL22948105 | 0.95 | L3MBTL1 (0.36) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL22949561 | 0.95 | L3MBTL1 (0.40) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL22949323 | 0.94 | L3MBTL1 (0.39) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL22949605 | 0.94 | L3MBTL1 (0.39) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL22947272 | 0.93 | MEN1 (0.37) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL22949559 | 0.91 | MEN1 (0.36) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL22948140 | 0.90 | L3MBTL1 (0.36) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL22947513 | 0.90 | L3MBTL1 (0.36) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL22947232 | 0.89 | CTRC (0.41) | MEN1KMT2AL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210036245-A1 | HETEROAROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210036245-A1 | HETEROAROMATIC COMPOUNDS | ETV6, FES, LEF1 | MEN1 2439/4885KMT2A 2115/4885L3MBTL1 3138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.