Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22947232 | 0.93 | CTRC (0.41) | CTRCALDH1A1CYP1A2SMN1; SMN2HSD17B10 | |
| SCHEMBL22947411 | 0.93 | L3MBTL1 (0.39) | ALDH1A1CYP1A2SMN1; SMN2HPGDMEN1 | |
| SCHEMBL22949534 | 0.93 | L3MBTL1 (0.39) | ALDH1A1CYP1A2SMN1; SMN2HPGDMEN1 | |
| SCHEMBL22947257 | 0.92 | CTRC (0.49) | CTRCALDH1A1CYP1A2SMN1; SMN2HSD17B10 | |
| SCHEMBL22947284 | 0.91 | MEN1 (0.41) | CTRCALDH1A1CYP1A2SMN1; SMN2HSD17B10 | |
| SCHEMBL22948106 | 0.89 | L3MBTL1 (0.36) | ALDH1A1CYP1A2HPGDMEN1KMT2A | |
| SCHEMBL22947272 | 0.89 | MEN1 (0.37) | ALDH1A1CYP1A2SMN1; SMN2HPGDMEN1 | |
| SCHEMBL23869125 | 0.89 | MEN1 (0.40) | ALDH1A1CYP1A2SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL22949564 | 0.88 | HPRT1 (0.36) | ALDH1A1CYP1A2SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL22949590 | 0.87 | CTRC (0.39) | CTRCALDH1A1CYP1A2SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210036245-A1 | HETEROAROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210036245-A1 | HETEROAROMATIC COMPOUNDS | ETV6, FES, LEF1 | CTRC 2608/4885ALDH1A1 752/4885CYP1A2 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.