Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1929525 | 0.88 | KAT6A (0.37) | NPC1KAT6AGSTP1 | |
| SCHEMBL1928266 | 0.86 | NPC1 (0.50) | NPC1KAT6AHTTGSTP1 | |
| SCHEMBL2285882 | 0.81 | NPC1 (0.35) | NPC1KAT6AHTTGSTP1 | |
| SCHEMBL1929575 | 0.78 | NPC1 (0.37) | NPC1KAT6AALDH1A1ALOX15GSTP1 | |
| SCHEMBL4618468 | 0.78 | KAT6A (0.35) | NPC1KAT6A | |
| SCHEMBL2290959 | 0.77 | TAS1R3 (0.37) | KAT6ASCN9A | |
| SCHEMBL2287389 | 0.76 | LMNA (0.39) | NPC1KAT6AALDH1A1ALOX15HTT | |
| SCHEMBL3230435 | 0.76 | SCN9A (0.39) | NPC1ALDH1A1ALOX15HTTSCN9A | |
| SCHEMBL3289575 | 0.76 | HTT (0.44) | HTT | |
| SCHEMBL2287310 | 0.75 | NPC1 (0.36) | NPC1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7999136-B2 | Amide compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-16 | — | — | US | disclosed |
| US-20100056640-A1 | AMIDE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-03-04 | — | — | US | disclosed |
| EP-2143709-A1 | AMIDE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2010-01-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056640-A1 | AMIDE COMPOUND AND USE THEREOF | NAT1, AGXT, HAX1 | NPC1 435/4885KAT6A 1091/4885ALDH1A1 2983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.