SCHEMBL229519

SCHEMBL229519

C=C(C)C(=O)OC[Si](C)(C)OC

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
ALDH1A1 P00352 2/20 0.44
THRB P10828 1/20 0.42
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7190871 0.85 TSHR (0.47) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL332509 0.85 TSHR (0.47) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL19499569 0.85 TSHR (0.40) TSHRALDH1A1THRB
SCHEMBL145163 0.83 TSHR (0.45) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL5401378 0.82 TSHR (0.44) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL1046024 0.82 TSHR (0.44) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL9915559 0.82 TSHR (0.44) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL82401 0.81 TSHR (0.47) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL4583359 0.80 TSHR (0.50) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL269321 0.80 TSHR (0.50) TSHRALDH1A1THRBPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4035649-B1 DENTAL ADHESIVE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-07-26 EP claimed
EP-3310792-B1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORP (US) 2021-07-21 EP claimed
CN-107743492-B Process for preparing acryloxysilanes 美国陶氏有机硅公司 2020-07-17 CN claimed
EP-3006599-B1 METHOD FOR COATING THE SURFACE OF A METAL SUBSTRATE SAFRAN LANDING SYSTEMS (FR) 2019-03-27 EP claimed
US-10066301-B2 Method of coating the surface of a metal substrate MESSIER-BUGATTI-DOWTY (FR) 2018-09-04 US claimed
US-20160102406-A1 METHOD OF COATING THE SURFACE OF A METAL SUBSTRATE MESSIER-BUGATTI-DOWTY (FR) 2016-04-14 US claimed
EP-3006599-A1 METHOD FOR COATING THE SURFACE OF A METAL SUBSTRATE Messier-Bugatti-Dowty (FR) 2016-04-13 EP claimed
EP-2024406-B1 A SILICONE ACRYLATE HYBRID COMPOSITION DOW CORNING (US) 2012-08-01 EP claimed
US-8124689-B2 Silicone acrylate hybride composition and method of making same DOW CORNING CORPORATION (US) 2012-02-28 US claimed
US-20100210745-A1 Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes REACTIVE SURFACES, LTD. (US) 2010-08-19 US claimed
WO-2007145996-A2 A SILICONE ACRYLATE HYBRID COMPOSITION DOW CORNING CORPORATION (US) 2007-12-21 WO claimed
EP-1298166-B1 RUBBER COMPOSITION JSR CORP (JP) 2007-02-21 EP claimed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US claimed
EP-1469002-A1 Method for stabilizing unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2004-10-20 EP claimed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US claimed
US-6699935-B2 A CROSSLINKED RUBBER PARTICLES CONTAINING CONJUGATED DIENE MONOMER, AROMATIC VINYL MONOMER AND MONOMER WITH AT LEAST TWO POLYMERIZABLE UNSATURATED GROUPS DISPERSED IN A CONJUGATED DIENE/AROMATIC VINYL COPOLYMER; RESIST TO ROLLING, SKID, WEAR JSR CORPORATION (JP) 2004-03-02 US claimed
US-6653404-B2 Melt processability; dimensional stability JSR CORPORATION (JP) 2003-11-25 US claimed
US-20030125467-A1 A crosslinked rubber particles containing conjugated diene monomer, aromatic vinyl monomer and monomer with at least two polymerizable unsaturated groups dispersed in a conjugated diene/aromatic vinyl copolymer; resist to rolling, skid, wear JSR CORPORATION (JP) 2003-07-03 US claimed
EP-1298166-A1 RUBBER COMPOSITION JSR Corporation (JP) 2003-04-02 EP claimed
US-20010053813-A1 Rubber compositions JSR CORPORATION (JP) 2001-12-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 TSHR 4650/4885ALDH1A1 402/4885THRB 4533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.