Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL915917 | 0.90 | NPC1 (0.44) | NPC1RAB9AKDM4EALDH1A1PARP1 | |
| SCHEMBL22952939 | 0.83 | KDM4E (0.45) | NPC1RAB9AKDM4EALDH1A1PARP1 | |
| SCHEMBL25360224 | 0.78 | RAB9A (0.52) | NPC1RAB9AKDM4EALDH1A1ELANE | |
| SCHEMBL21822490 | 0.77 | CSF1R (0.39) | NPC1RAB9AKDM4EALDH1A1ELANE | |
| SCHEMBL12528680 | 0.76 | PBRM1 (0.40) | NPC1RAB9AKDM4EALDH1A1PARP1 | |
| SCHEMBL2333007 | 0.75 | RAB9A (0.69) | NPC1RAB9AKDM4EALDH1A1ELANE | |
| SCHEMBL13587068 | 0.74 | ELANE (0.54) | NPC1RAB9AKDM4EALDH1A1ELANE | |
| SCHEMBL12927380 | 0.73 | RAB9A (0.58) | NPC1RAB9AKDM4EALDH1A1ELANE | |
| SCHEMBL12528298 | 0.73 | RAB9A (0.46) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12528466 | 0.73 | S1PR1 (0.41) | RAB9AKDM4EALDH1A1PARP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210033886-A1 | LENS FOR SPECTACLES AND SPECTACLES | FUJIFILM CORPORATION (JP) | 2021-02-04 | — | — | US | disclosed |