Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22953385 | 0.85 | DRD1 (0.36) | HTR2ADRD2DRD1 | |
| SCHEMBL22953388 | 0.80 | HTR2A (0.43) | HTR2ADRD2DRD1 | |
| SCHEMBL22952974 | 0.77 | DRD2 (0.30) | DRD2DRD1 | |
| SCHEMBL22952984 | 0.72 | DRD2 (0.32) | HTR2ADRD2DRD1 | |
| SCHEMBL22952978 | 0.67 | DRD1 (0.34) | HTR2ADRD2DRD1 | |
| SCHEMBL22953387 | 0.65 | DRD1 (0.35) | DRD2DRD1 | |
| SCHEMBL22952970 | 0.65 | SLC6A4 (0.31) | — | |
| SCHEMBL16938669 | 0.64 | HTR2A (0.60) | HTR2ADRD2DRD1 | |
| SCHEMBL3672464 | 0.64 | HTR2A (0.60) | HTR2ADRD2DRD1 | |
| SCHEMBL29383346 | 0.64 | HTR2A (0.60) | HTR2ADRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021922-A1 | COMPOUNDS AND METHODS FOR TREATING FIBROTIC PATHOLOGIES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2021-02-04 | — | — | WO | disclosed |