Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 3/20 | 0.35 |
| ▸ | DRD5 | P21918 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22952970 | 0.87 | SLC6A4 (0.31) | SLC6A4HRH3 | |
| SCHEMBL22952978 | 0.86 | DRD1 (0.34) | DRD1DRD5DRD2SLC6A4 | |
| SCHEMBL22953389 | 0.83 | HTR2A (0.34) | DRD1DRD5 | |
| SCHEMBL22952972 | 0.80 | DRD1 (0.34) | DRD1DRD5DRD2SLC6A4HRH3 | |
| SCHEMBL22953385 | 0.78 | DRD1 (0.36) | DRD1DRD5DRD2SLC6A4 | |
| SCHEMBL22952988 | 0.71 | DRD1 (0.33) | DRD1DRD5DRD2SLC6A4 | |
| SCHEMBL22952975 | 0.70 | DRD2 (0.36) | DRD1DRD2SLC6A4HRH3 | |
| SCHEMBL22953390 | 0.68 | HTR2A (0.36) | DRD1DRD2 | |
| SCHEMBL22952980 | 0.67 | SLC6A4 (0.32) | SLC6A4HRH3 | |
| SCHEMBL22952969 | 0.65 | HTR2A (0.35) | DRD1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021922-A1 | COMPOUNDS AND METHODS FOR TREATING FIBROTIC PATHOLOGIES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2021-02-04 | — | — | WO | disclosed |