Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22952985 | 0.85 | PARP1 (0.32) | DRD1PARP1KIF11 | |
| SCHEMBL22952988 | 0.85 | DRD1 (0.33) | DRD2DRD1PARP1HTR2CHTR2B | |
| SCHEMBL22952989 | 0.82 | PARP1 (0.43) | PARP1HTR2AKIF11 | |
| SCHEMBL22953346 | 0.79 | PARP1 (0.33) | DRD2DRD1PARP1KIF11 | |
| SCHEMBL22952969 | 0.72 | HTR2A (0.35) | DRD2DRD1HTR2A | |
| SCHEMBL22953343 | 0.66 | PARP1 (0.41) | DRD2DRD1PARP1KIF11 | |
| SCHEMBL22953345 | 0.64 | DRD1 (0.34) | DRD2DRD1PARP1HTR2BKIF11 | |
| SCHEMBL22953342 | 0.64 | PARP1 (0.33) | PARP1KIF11 | |
| SCHEMBL22952987 | 0.63 | PARP1 (0.41) | DRD1PARP1HTR2AHTR2CKIF11 | |
| SCHEMBL22953386 | 0.63 | PARP1 (0.39) | PARP1HTR2AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021922-A1 | COMPOUNDS AND METHODS FOR TREATING FIBROTIC PATHOLOGIES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2021-02-04 | — | — | WO | disclosed |