Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 7/20 | 0.33 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | RECQL | P46063 | 4/20 | 0.32 |
| ▸ | BLM | P54132 | 3/20 | 0.32 |
| ▸ | DRD5 | P21918 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | THPO | P40225 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22952985 | 0.85 | PARP1 (0.32) | DRD1PARP1KIF11 | |
| SCHEMBL22952984 | 0.85 | DRD2 (0.32) | DRD1DRD2HTR2BPARP1HTR2C | |
| SCHEMBL22952989 | 0.82 | PARP1 (0.43) | KDM4ECYP3A4NFKB1THPOHSD17B10 | |
| SCHEMBL22953345 | 0.79 | DRD1 (0.34) | DRD1DRD2KDM4ERECQLBLM | |
| SCHEMBL22952978 | 0.75 | DRD1 (0.34) | DRD1DRD2DRD5SLC6A2SLC6A4 | |
| SCHEMBL22953385 | 0.72 | DRD1 (0.36) | DRD1DRD2KDM4ERECQLBLM | |
| SCHEMBL22953387 | 0.71 | DRD1 (0.35) | DRD1DRD2DRD5SLC6A4 | |
| SCHEMBL22953343 | 0.66 | PARP1 (0.41) | DRD1DRD2KDM4ERECQLCYP3A4 | |
| SCHEMBL22953346 | 0.64 | PARP1 (0.33) | DRD1DRD2PARP1KIF11 | |
| SCHEMBL22953386 | 0.63 | PARP1 (0.39) | PARP1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021922-A1 | COMPOUNDS AND METHODS FOR TREATING FIBROTIC PATHOLOGIES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2021-02-04 | — | — | WO | disclosed |